Feedback circuits in regulation of digestion and energy storage

How does the brain control food intake and energy homeostasis?

We now understand that the meal-terminating systems in the brainstem as well as the brain reward circuits work in conjunction with the hypothalamus to mediate the overall control of food intake and energy homeostasis.

Does the hindbrain control food intake and energy balance?

We frame this information in the context of new atlases of hindbrain neuronal populations and develop a model of the hindbrain circuits that control food intake and energy balance, suggesting important areas for additional research.

How does gut regulation work?

This gut regulation is carried out by different hormones secreted from endocrine cells in the gastrointestinal tract, as well as by several neural pathways that communicate information from the signals responsible for the regulation of food intake and energy expenditure.

Do brain glucose and energy-sensing systems control food intake and energy balance?

Hence, the brain glucose- and energy-sensing systems may be mainly involved in defending against large swings in blood glucose (e.g., defending against hypoglycemia) rather than serving as a primary controller of food intake and energy balance.

Do hypothalamic circuits control ingestive behaviour?

While these hypothalamic circuits play crucial roles in energy balance, they do not directly control ingestive behaviour.

What is a classical physiological feedback model?

Classical physiological feedback models propose that eating behavior is stimulated and inhibited by internal signaling systems (for the drive and suppression of eating, respectively) to maintain stability of the internal environment (usually energy or nutrient stores).